Chemical
Tranexamic Acid
Catagory
Active Ingredients
Synthetic amino acid derivative (trans-4-(aminomethyl)cyclohexanecarboxylic acid).
Blocks plasminogen/plasmin pathway to treat stubborn melasma and post-inflammatory hyperpigmentation.
Mechanism Of Action
Lysine analog that competitively blocks plasminogen/plasmin pathway activation in keratinocytes, preventing downstream release of arachidonic acid, prostaglandins, and basic fibroblast growth factor (bFGF) that stimulate melanogenesis.
Conditions Assisted
Hyperpigmentation, Melasma, Post-Inflammatory Erythema (PIE), Post-Inflammatory Hyperpigmentation (PIH), Rosacea-Associated Redness
Side Effects
Very mild; occasional temporary dryness or slight tingling when combined with exfoliating acids.
Pairs Well With
Niacinamide (Vitamin B3), Alpha Arbutin, Kojic Acid, Azelaic Acid, Ascorbic Acid (Vitamin C)